发明名称 CRYSTALLINE FORM OF N-((1-(3-(1,2,3-TRIAZOL-1-YL)PROPYL)PIPERIDINE-4-YL)METHYL)-4-AMINO-5-CHOLORO-2-METHOXYBENZAMIDE DERIVATIVES AND PREPARATION METHOD THEREOF
摘要 <p>The present invention relates to a crystalline form, solvate and hydrate of N-((1-(3-(1,2,3-triazol-1-yl)propyl)piperidine-4-yl)methyl)-4-amino-5-chloro-2-methoxybenzamide derivatives and preparation method thereof indicated by chemical formula 1 below. A crystalline form refers to a crystalline sold that does not include a fixed molecular rate of solvent molecules within the crystalline lattice, in other words, a crystalline sold, not solvate. The present invention clearly indicates solvate or more specifically hydrate. According to a specific example of the present invention, solvate refers to a compound or condensation material formed by one or more solvent molecules, in other words, N-((1-(3-(1,2,3-triazol-1-yl)propyl)piperidine-4-yl)methyl)-4-amino-5-choloro-2-methoxybenzamide derivatives or one or more solvent molecules. The solvate is a typical crystalline sold having a fixed mole rate of solvent or solute. The most well-known solvent can include water, methanol, ethanol, isopropanol or acetate acid. If the solvent is water, the formed solvate is called hydrate.</p>
申请公布号 KR20150084155(A) 申请公布日期 2015.07.22
申请号 KR20140003858 申请日期 2014.01.13
申请人 DONG-A ST CO., LTD. 发明人 IM, WEON BIN;CHOI, SUNG HAK;KWAK, WOO YOUNG;CHOI, SUN HO
分类号 C07D403/06;A61K31/454;A61P1/00;A61P9/00;A61P25/00 主分类号 C07D403/06
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