| 发明名称 |
CHEMICAL PROCESS FOR OPENING RING COMPOUNDS |
| 摘要 |
<p>It is described a process for the opening of lactone or lactam rings useful in the synthesis of pharmaceutically active compounds and the intermediates thereof, particularly Aliskiren. It has found that by selecting a type of solvent it is possible to obtain excellent yields and high optical and chemical purity of the isolated products.</p> |
| 申请公布号 |
EP2736875(B1) |
申请公布日期 |
2015.07.22 |
| 申请号 |
EP20120738468 |
申请日期 |
2012.07.25 |
| 申请人 |
CHEMO IBÉRICA, S.A. |
发明人 |
CARCONE, LUCA;MAGRONE, DOMENICO;BARRECA, GIUSEPPE;RASPARINI, MARCELLO;LIMING, HUAN |
| 分类号 |
C07C231/02;C07C231/14;C07C237/22;C07C271/22 |
主分类号 |
C07C231/02 |
| 代理机构 |
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