发明名称 |
SINGLE DOMAIN ANTIBODY WITH C-TERMINAL MODIFICATION |
摘要 |
The invention pertains to an isolated VH single domain antibody comprising a C-terminal modification, where the C-terminal modification comprises a deletion of at least one amino acid residue that eliminates the interaction of a pre-existing antibody with the single domain antibody without interfering with the binding of the single domain antibody with its target. |
申请公布号 |
EP2895510(A2) |
申请公布日期 |
2015.07.22 |
申请号 |
EP20130766855 |
申请日期 |
2013.09.13 |
申请人 |
NOVARTIS AG |
发明人 |
LOEW, ANDREAS;EBERSBACH, HILMAR |
分类号 |
C07K16/00;A61P43/00;C07K16/18 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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