发明名称 |
MODULATION OF PODOPLANIN MEDIATED PLATELET ACTIVATION |
摘要 |
The present invention relates generally to the use of modulators of podoplanin (PDPN) mediated platelet activation. For example, an agonist or mimic of podoplanin (PDPN)/C-type lectin-like receptor 2 (CLEC-2) signaling may be used to inhibit vascular leakage or promote vascular integrity. Alternatively, an antagonist of podoplanin (PDPN)/C-type lectin-like receptor 2 (CLEC-2) signaling may be used to inhibit platelet activation. |
申请公布号 |
EP2895184(A1) |
申请公布日期 |
2015.07.22 |
申请号 |
EP20130836620 |
申请日期 |
2013.09.12 |
申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
XIA, LIJUN |
分类号 |
A61K38/00;A61K31/661;A61K38/17;A61K45/06;A61P7/04;C07K14/47;C07K16/18;C07K16/28;C12N15/113 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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