发明名称 |
PYRROLO[2,1-C][1,4]BENZODIAZEPINE LINKED IMIDAZO[1,5-A]PYRIDINE CONJUGATES AS POTENTIAL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF |
摘要 |
<p>The present invention provides a compound of general formula 7, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine linked imidazo[1,5-a]pyridine conjugates attached through a piperazine moiety and different alkane spacers of general formula 7 wherein R represents H, OCH3, CF3, CN, F or Cl; n=3, 4, 5 or 6.</p> |
申请公布号 |
EP2648757(B1) |
申请公布日期 |
2015.07.22 |
申请号 |
EP20110719636 |
申请日期 |
2011.03.23 |
申请人 |
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH |
发明人 |
AHMED, KAMAL;GADUPUDI, RAMAKRISHNA;PAIDAKULA, RAJU;AYINAMPUDI, VENKATA, SUBBA, RAO;ARUTLA, VISWANATH;GORRE, BALAKISHAN |
分类号 |
A61K47/48;A61P35/00;C07D471/04;C07D519/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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