| 发明名称 | Delivery of dsRNA to arthropods | ||
| 摘要 | The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention. | ||
| 申请公布号 | US9085770(B2) | 申请公布日期 | 2015.07.21 |
| 申请号 | US201414521184 | 申请日期 | 2014.10.22 |
| 申请人 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION | 发明人 | Whyard Steven;Cameron Fiona Helen;Moghaddam Minoo;Lockett Trevor J. |
| 分类号 | C07H21/02;C07H21/04;A61K48/00;C12N15/113;A01K67/033;C12N15/11;A01N57/16;A61K31/713;A61K38/00 | 主分类号 | C07H21/02 |
| 代理机构 | Cooper & Dunham LLP | 代理人 | White John P.;Gershik Gary J.;Cooper & Dunham LLP |
| 主权项 | 1. A method of reducing the level of a target RNA in a coleopteran or hymenopteran insect comprising feeding to the insect in a larval stage a composition comprising a dsRNA molecule produced in a transgenic organism expressing the dsRNA and a lipid containing compound as a transfection promoting agent, wherein the dsRNA molecule specifically reduces the level of the target RNA in a cell of the insect. | ||
| 地址 | Campbell AU | ||