发明名称 |
MICROPARTICLES CONTAINING BIODEGRADABLE POLYMER AND CATIONIC POLYSACCHARIDE FOR USE IN IMMUNOGENIC COMPOSITIONS |
摘要 |
<p>Immunogenic compositions are described herein which comprise microparticles that further comprise a biodegradable polymer. The microparticle compositions also comprise a cationic polysaccharide and an immunological species selected from an antigen, an immunological adjuvant and a combination thereof. Also described are methods of making such compositions and methods of administering such compositions. Methods of modulating the release rate of immunological species from microparticles are also described. These methods comprise varying the ratio of the cationic polysaccharide relative to the biodegradable polymer within the microparticles.</p> |
申请公布号 |
CA2643322(C) |
申请公布日期 |
2015.07.21 |
申请号 |
CA20072643322 |
申请日期 |
2007.02.24 |
申请人 |
NOVARTIS AG |
发明人 |
O'HAGAN, DEREK T.;SINGH, MANMOHAN;WENDORF, JANET;KAZZAZ, JINA;MALYALA, PADMA |
分类号 |
A61K9/16 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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