发明名称 2,3-diphenyl-valeronitrile derivatives, method for the production thereof and use thereof as herbicides and plant growth regulators
摘要 The invention describes compounds of formula (I),; processes for preparing the compounds and methods of using the compounds as herbicides for the control of harmful plants or as plant growth regulators.
申请公布号 US9084425(B2) 申请公布日期 2015.07.21
申请号 US201214131891 申请日期 2012.07.11
申请人 BAYER INTELLECTUAL PROPERTY GMBH 发明人 Mosrin Marc;Jakobi Harald;Angermann Alfred;Gatzweiler Elmar;Häuser-Hahn Isolde;Heinemann Ines;Rosinger Christopher Hugh;Lehr Stefan;Schnatterer Stefan
分类号 A01N43/80;A01N43/56;A01N43/16;A01N43/32;A01N37/42;A01N37/34;C07C255/62;C07C255/66;C07D319/06;C07D231/12;C07D231/16;C07D231/20;C07D261/08;C07C255/40;C07C255/56;C07C255/41 主分类号 A01N43/80
代理机构 Miles and Stockbridge 代理人 Miles and Stockbridge
主权项 1. A compound of formula (I) and/or a salt thereofin which L represents a radical of formula A1 represents oxygen, sulphur or ═N—RA, B1 represents a radical of formulae (B1) to (B14), A2 represents a radical of formulae (A1) to (A12), B2 represents hydroxy, thio, halogen or a group of the formula OR33, OM, SR34, SM or —NRBRC, W1 and W6 independently of one another each represent a divalent group oxygen, sulphur or a group of the formula NH, N—[(C1-C4)-alkyl], C═O (carbonyl), S═O (sulphinyl), SO2 (sulphonyl) or CR35R36, W2, W3, W4, W5 and W7 independently of one another each represent the divalent group oxygen, sulphur or a group of the formula NH, N—[(C1-C4)-alkyl], C═O (carbonyl), S═O (sulphinyl) or SO2 (sulphonyl), Q1, Q2, Q3, Q4, Q5, Q6, Q7, Q8 and Q9 independently of one another each represent hydroxy, thio, halogen or a group of the formula OR37, SR38, SM or OM, M represents an equivalent of a cation, RA, RB and RC independently of one another each represent hydrogen, hydroxy, (C1-C4)-alkoxy, (C1-C4)-alkyl, (C1-C4)-haloalkyl, phenyl or benzyl, where each of the two last-mentioned radicals is optionally mono- or polysubstituted by identical or different substituents, or —NR*R**, where R* and R** independently of one another each represent H, (C1-C8)-alkyl, (C2-C8)-alkenyl, (C2-C8)-alkynyl, (C1-C4)-alkoxy-(C1-C4)-alkyl, (C1-C6)-alkanoyl, [(C1-C4)-haloalkyl]carbonyl, [(C1-C4)-alkoxy]carbonyl, [(C1-C4)-haloalkoxy]carbonyl, (C3-C6)-cycloalkyl, (C3-C6)-cycloalkyl-(C1-C4)-alkyl, phenyl, or phenyl-(C1-C4)-alkyl, where each of the 4 last-mentioned radicals is unsubstituted in the cycle or substituted by at least one radical from the group consisting of halogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy and (C1-C4)-haloalkoxy or, in the case of cycloalkyl, also oxo, orR* and R** together with the nitrogen atom represent a 3- to 8-membered heterocycle which, in addition to the nitrogen atom, may contain one or two further ring heteroatoms from the group consisting of N, O and S and which may be unsubstituted or substituted by at least one radical from the group consisting of (C1-C4)-alkyl, (C1-C4)-haloalkyl and oxo, (R1)m represents m substituents R1, where R1, if m=1, or each of the substituents R1, if m is greater than 1, independently of the others represents halogen, cyano, nitro, hydroxy, (C1-C8)-alkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, (C1-C8)-alkoxy, (C1-C8)-alkylthio, (C1-C8)-alkylsulphinyl, (C1-C8)-alkylsulphonyl, (C1-C6)-haloalkyl, (C1-C6)-haloalkoxy, (C1-C6)-haloalkylthio, (C1-C6)-haloalkylsulphinyl, (C1-C6)-haloalkylsulphonyl, (C2-C6)-haloalkenyl, (C2-C6)-haloalkynyl, (C1-C6)-alkoxy-(C1-C4)-alkyl, (C1-C6)-haloalkoxy-(C1-C4)-alkyl, (C3-C6)-cycloalkyl which is optionally substituted by at least one radical from the group consisting of halogen and (C1-C4)-alkyl, (C3-C6)-cycloalkoxy which is optionally substituted by at least one radical from the group consisting of halogen and (C1-C4)-alkyl, or a radical of formula C(O)OR39, C(O)NR40R41, C(O)-Het1, NR42R43 or Het2 or where in each case two groups R1 located ortho at the ring together are a group of the formula —Z1-A*-Z2 in whichA* represents an alkylene group having from 1 to 4 carbon atoms which is optionally substituted by at least one radical from the group consisting of halogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy and (C1-C4)-haloalkoxy,Z1 represents a direct bond, O or S andZ2 represents a direct bond, O or S,where the group —Z1-A*-Z2 together with the carbon atoms, attached to the group, of the phenyl ring form a fused-on 5- or 6-membered ring, and (R2)n represents n substituents R2, where R2, if n=1, or each of the substituents R2, if n is greater than 1, independently of one another represents halogen, cyano, nitro, hydroxy, (C1-C8)-alkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, (C1-C8)-alkoxy, (C1-C8)-alkylthio, (C1-C8)-alkylsulphinyl, (C1-C8)-alkylsulphonyl, (C1-C6)-haloalkyl, (C1-C6)-haloalkoxy, (C1-C6)-haloalkylthio, (C1-C6)-haloalkylsulphinyl, (C1-C6)-haloalkylsulphonyl, (C2-C6)-haloalkenyl, (C2-C6)-haloalkynyl, (C1-C6)-alkoxy-(C1-C4)-alkyl, (C1-C6)-haloalkoxy-(C1-C4)-alkyl, (C3-C6)-cycloalkyl which is optionally substituted by at least one radical from the group consisting of halogen and (C1-C4)-alkyl, (C3-C6)-cycloalkoxy which is optionally substituted by at least one radical from the group consisting of halogen and (C1-C4)-alkyl, or a radical of formula C(O)OR44, C(O)NR45R46, C(O)-Het3, NR47R48 or Het4 orwhere in each case two groups R2 located ortho at the ring together are a group of formula —Z3-A**-Z4 in whichA** represents an alkylene group having from 1 to 4 carbon atoms which is optionally substituted by at least one radical from the group consisting of halogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy and (C1-C4)-haloalkoxy,Z3 represents a direct bond, O or S andZ4 represents a direct bond, O or S,where the group —Z3-A**-Z4 together with the carbon atoms, attached to the group, of the phenyl ring form a fused-on 5- or 6-membered ring, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19 and R20 independently of one another each represent hydrogen, halogen, cyano, nitro, hydroxy, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy, (C1-C4)-haloalkoxy, (C1-C4)-alkoxy-(C1-C4)-alkyl, (C1-C4)-haloalkoxy-(C1-C4)-alkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C3-C6)-cycloalkoxy, (C2-C6)-alkenyl, (C2-C6)-haloalkenyl, (C2-C6)-alkynyl, (C2-C6)-haloalkynyl, (C1-C4)-alkylthio, (C1-C4)-alkylsulphonyl, (C1-C4)-alkylsulphinyl, phenyl which is optionally substituted, or a group C(O)OR49, C(O)NR50R51, C(O)Het5, NR52R53 or Het6 or R3 and R5 in the group of formula (B1) or (A1) together represent a divalent bridge of a straight-chain alkylene or alkenylene group having 2 or 3 carbon atoms, where a CH2 group in the chain may also be replaced by an oxygen atom and where a CH2 group or CH group in the chain is optionally substituted by at least one radical from the group consisting of (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy and (C1-C4)-haloalkoxy, R21 represents hydrogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl or a group C(O)OR54, C(O)NR55R56, C(O)Het7, NR57R58 or Het8, R22 represents hydrogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C1-C4)-alkylthio, (C1-C4)-alkylsulphonyl, (C1-C4)-alkylsulphinyl or a group of formula C(O)OR59, C(O)NR60R61, C(O)Het9 NR62R63 or Het10, R23 and R29 independently of one another each represent hydrogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C1-C4)-alkoxy or (C1-C4)-haloalkoxy, R24 and R30 independently of one another each represent hydrogen, halogen, cyano, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C1-C4)-alkoxy or (C1-C4)-haloalkoxy, R25, R26, R31 and R32 independently of one another each represent hydrogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy, (C1-C4)-haloalkoxy, (C1-C4)-alkoxy-(C1-C4)-alkyl, (C1-C4)-haloalkoxy-(C1-C4)-alkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C3-C6)-cycloalkoxy, (C2-C6)-alkenyl, (C2-C6)-haloalkenyl, (C2-C6)-alkynyl, (C2-C6)-haloalkynyl, (C1-C4)-alkylthio, (C1-C4)-alkylsulphonyl, (C1-C4)-alkylsulphinyl, NR64R65 or Het11, R27 represents hydrogen, (C1-C6)-alkyl, (C1-C4)-haloalkyl, (C3-C6)-cycloalkyl or (C3-C6)-halocycloalkyl, R28 represents hydrogen, (C1-C6)-alkyl, (C1-C4)-haloalkyl or a radical of the formula C(O)OR66, R33, R34, R37 and R38 independently of one another each represent (C1-C8)-alkyl, (C3-C6)-cycloalkyl, phenyl, where each of the three last-mentioned radicals in each case independently of the others is unsubstituted or substituted by at least one radical from the group consisting of halogen, cyano, nitro, hydroxy, (C1-C4)-alkoxy, (C1-C4)-alkylthio and, in the case of a cycloalkyl or phenyl radical as parent radical, also (C1-C4)-alkyl and (C1-C4)-haloalkyl, or a group of formula —C(O)R67, —C(O)OR68, —C(O)NR69R70, —C(O)Het12 or —SO2R71, R35 and R36 independently of one another are each defined as R3, R39, R44, R49, R54, R59 and R66 independently of one another each represent hydrogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C2-C4)-alkenyl, (C2-C4)-haloalkenyl, (C2-C4)-alkynyl or M, R40, R41, R42, R43, R45, R46, R47, R48, R50, R51, R52, R53, R55, R56, R57, R58, R60, R61, R62, R63, R64, R65, R69 and R70 independently of one another each represent hydrogen, (C1-C6)-alkyl, (C2-C6)-alkenyl or (C2-C6)-alkynyl, where each of the 3 last-mentioned radicals in each case independently of the others is unsubstituted or substituted by at least one radical from the group consisting of halogen, nitro, cyano and phenyl, which is optionally substituted, or (C3-C6)-cycloalkyl or phenyl, where each of the 2 last-mentioned radicals in each case independently of the other is unsubstituted or substituted by at least one radical from the group consisting of halogen, nitro, cyano, (C1-C4)-alkyl, (C1-C4)-haloalkyl, phenyl and benzyl, where each of the 2 last-mentioned radicals is optionally substituted, R67 represents hydrogen, (C1-C8)-alkyl or (C1-C8)-haloalkyl, where each of the 2 last-mentioned radicals independently of the other is optionally interrupted in the alkyl moiety by oxygen or sulphur, or phenyl or benzyl, where each of the 2 last-mentioned radicals independently of the other is unsubstituted or substituted by at least one radical from the group consisting of halogen, cyano, (C1-C4)-alkyl, (C2-C4)-alkenyl, (C2-C4)-alkynyl, (C3-C6)-cycloalkyl, (C1-C4)-haloalkyl and (C3-C6)-halocycloalkyl, R68 represents (C1-C8)-alkyl, (C1-C8)-haloalkyl, (C3-C6)-cycloalkyl, (C3-C6)-halocycloalkyl, (C2-C8)-alkenyl, (C2-C8)-haloalkenyl or (C2-C4)-alkynyl, R71 represents (C1-C6)-alkyl, (C1-C6)-haloalkyl or phenyl or benzyl, where each of the 2 last-mentioned radicals independently of the other is unsubstituted or substituted by at least one radical from the group consisting of halogen, cyano, (C1-C4)-alkyl, (C2-C4)-alkenyl, (C2-C4)-alkynyl, (C3-C6)-cycloalkyl, (C1-C4)-haloalkyl and (C3-C6)-halocycloalkyl, Het1, Het2, Het3, Het4, Het5, Het6, Het7, Het8, Het9, Het10, Het11 and Het12 independently of one another are each a saturated or partially unsaturated radical of a heterocycle having from 3 to 9 ring atoms and at least one nitrogen atom as ring heteroatom at position 1 of the ring and optionally 1, 2 or 3 further ring heteroatoms from the group consisting of N, O and S, where the radical of the heterocycle is attached at the nitrogen atom in position 1 of the ring to the remainder of the molecule of the compound of formula (I) and where the heterocycle is unsubstituted or substituted by at least one radical from the group consisting of halogen, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy, (C1-C4)-haloalkoxy, (C1-C4)-alkylthio and oxo, and m, n independently of one another each represent 0, 1, 2, 3, 4 or 5.
地址 Monheim DE