发明名称 2-PHENYLAMINO-4-(PYRIDIN-3-YL)-6-PERFLUOROALKYLPYRIMIDINES
摘要 The present invention relates to novel derivatives of 2-phenylamino-pyrimidine useful as tyrosine kinase inhibitors, particularly to 2-phenylamino-4-(pyridin-3-yl)-6-perfluoroalkyl-pyrimidines and intermediates for preparing thereof. Still more specifically the present invention relates to compound of general formula (I)wherein:n is an integer from 0 to 2,X is a substituent chosen from the group consisting of:wherein n is 0 or 1,X is OCH3 in position 4, or OCH3 in position 3, 4 and 5,and novel intermediates for preparing the aforementioned compounds.
申请公布号 LV14984(B) 申请公布日期 2015.07.20
申请号 LV20130000125 申请日期 2013.09.04
申请人 GRINDEKS, A/S 发明人 LAVRINOVI&Ccaron,S EDVARDS;TERENTJEVA SVETLANA;L&Umacr,SIS VIESTURS;MUCENIECE DZINTRA
分类号 C07D401/04;A61K31/506 主分类号 C07D401/04
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