METHOD OF CONTROL OF PRODUCTION OF ENCAPSULATED ENZYME PREPARATIONS

摘要

FIELD: biotechnology.SUBSTANCE: method comprises production of enzyme preparations by submerged cultivation of microorganisms of enzyme preparations with continuous aeration with sterile air and mechanical agitation throughout the volume of the fermenter; receiving the hot air in the condenser of the heat pump with discharge of one its part to the spray drier, and the other - for heating water; returning the exhaust air after the recuperative heat exchanger and evaporator of the heat pump to the condenser to form recirculation loop; alternate supplying the obtained culture fluid under pressure for filtration to two filters mounted in parallel with the countercurrent aqueous regeneration of the filter element, that alternately operate in the mode of separation with the discharge of the precipitate and regeneration; discharge of culture fluid filtrate with the content of solids of 5-8% first in the storage collector and then to the spray drier using a vapour-compression heat pump; draining the condensate from the evaporator, followed by feeding under pressure to the filter operating in the regeneration mode.EFFECT: invention enables to improve the quality and properties of the encapsulated enzyme preparations, to increase the shelf life of encapsulated enzyme preparations, as well as to improve energy efficiency.1 dwg, 2 ex