Compuestos derivados de n-[(3-cloro-6,7,10,11-tetrahidro-9-metil-7,11-metanocicloocta[b]quinolin-12-il)amino]-9,10-dihidro-4,5-dihidroxi-9,10-dioxoantraceno-2-carboxamida; procedimiento para prepararlos; composicion farmaceutica; compuestos intermediarios; y uso para la prevencion y/o tratamiento de la enfermedad de alzheimer.

摘要

The compounds of formula (I), or its pharmaceutically acceptable salts, or any stereoisomer or mixture thereof, wherein: R1 is a (C1-C2) alkyl radical; R2 and R3 are radicals independently selected from the group consisting of F, CI and methyl R4 is H or OH; A is a birradical selected from the group consisting of —(CH2)n— and —(CH2)-phenyl-(CH2)—; t is an integer from 0 to 1; and n is an integer from 8 to 15, are useful for the treatment of Alzheimer's disease.