| 发明名称 |
ADAMANTYL-ACETAMIDE DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME 11-- 1- |
| 摘要 |
<p>The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.</p> |
| 申请公布号 |
HK1102593(A1) |
申请公布日期 |
2015.07.17 |
| 申请号 |
HK20070108098 |
申请日期 |
2007.07.25 |
| 申请人 |
ABBVIE INC. |
发明人 |
LINK, JAMES T.;PLIUSHCHEV, MARINA A.;ROHDE, JEFFREY J.;WODKA, DARIUSZ;PATEL, JYOTI R.;SHUAI, QI |
| 分类号 |
C07D;A61K;C07C237/04;C07C237/24;C07D207/02;C07D209/08;C07D213/06;C07D213/24;C07D213/72;C07D213/74;C07D213/85;C07D223/16;C07D253/06;C07D257/04;C07D277/64;C07D295/15;C07D295/185;C07D471/08;C07D491/04 |
主分类号 |
C07D |
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