FUSION PROTEINS CONTAINING INSULIN-LIKE GROWTH FACTOR-1 AND EPIDERMAL GROWTH FACTOR AND VARIANTS THEREOF AND USES THEREOF

摘要

Fusion proteins comprising cytokines, particularly insulin- like growth factor- 1 (IGF-1) and variants thereof, epidermal growth factor (EGF), and other ligands to the EGF receptor, are provided. The fusion proteins further comprise SEQ ID NO: l or other segments having lysine, glutamic acid, or aspartic acid residues. Uses for the fusion proteins are also provided.