INDUCING AND MEASURING MYOCARDIAL OXYGENATION CHANGES AS A MARKER FOR HEART DISEASE

摘要

The present disclosure relates to a method of assessing heart function and a system for assessing heart function. In detail, the present disclosure relates to a measuring a change in oxygenation or blood flow in the heart of the subject in response to a breathing maneuver and comparing the change in oxygenation or blood flow to a control. The change in oxygenation may be measured by segmenting an image of a heart, determining the signal intensity of a region of interest in a segment of the image and comparing the signal intensity to a control. An abnormal change in oxygenation blood flow or signal intensity in the heart compared to the control is indicative of reduced heart function. The disclosure further relates to a system for diagnosing heart disease which comprises an imaging device and processor configured to assess heart function.

主权项

1. A method of assessing heart function in a subject comprising:
measuring a change in at least one of oxygenation and blood flow in the heart of the subject in response to at least one breathing maneuver; comparing the change in the at least one of measured oxygenation and blood flow compared to a control; and assessing heart function in accordance with the comparison result, wherein an abnormal response in at least one of oxygenation and blood flow in the heart compared to the control is indicative of reduced heart function.