发明名称 BENZOTHIAZOLE OR BENZOXAZOLE COMPOUNDS AS SUMO ACTIVATORS
摘要 Provided are benzothiazole and benzoxazole derivatives that are SUMO activators, which can enhance SUMOylation of SERCA2a, and pharmaceutical compositions containing the same, which are useful in the treatment of heart failure, cardiovascular diseases, cancer, neurodegenerative disorders, viral infection, bacterial infection, liver disease, inflammation, and other diseases.
申请公布号 WO2014036242(A3) 申请公布日期 2015.07.16
申请号 WO2013US57264 申请日期 2013.08.29
申请人 MOUNT SINAI SCHOOL OF MEDICINE 发明人 DAHL, RUSSELL;LEE, AH YOUNG;KHO, CHANGWON;HAJJAR, ROGER J.
分类号 A61K31/428;A61K31/4245;C07D277/62 主分类号 A61K31/428
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