| 主权项 |
1. A compound of Formula I:wherein
R1, R2, R3, and R4 are each independently hydrogen, hydroxy, halogen, C1-4 alkyl, substituted C1-4 alkyl, C1-4 alkoxy, substituted C1-4 alkoxy, —CN, —CORx, —CO2Rx, —SO2Rx, or —NRxRy;
wherein Rx and Ry are each independently H or optionally substituted C1-4alkyl, or Rx and Ry taken together with the nitrogen to which they are attached form an optionally substituted monocyclic heterocycloalkyl ring; X is absent, or is C1-6 alkylene, wherein one carbon unit of said alkylene is optionally replaced with —O—, —S—, —SO—, —NRa—, —SO2—, or —CO—;
wherein Ra is hydrogen or C1-4 alkyl; G4, G5, G6, and G7 are each independently CR10 or N;
wherein each R10 is independently hydrogen, hydroxy, halogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, or C1-4 haloalkoxy; Y is absent, or is C1-6 alkylene, wherein one carbon unit of said alkylene is optionally replaced with —O—, —S—, —NH—, —SO—, —SO2—, —CO—, —CO2—, —CONH—, —NHCO—, —NHSO2—, or —SO2NH—; Ring A is a 5-membered heteroaryl ring; each R5 is independently C1-6 alkyl, substituted C1-6 alkyl, C1-6 alkoxy, substituted C1-6 alkoxy, C3-8 cycloalkyl, substituted C3-8 cycloalkyl, C3-8 cycloalkoxy, substituted C3-8 cycloalkoxy, hydroxyl, halogen, —NRmRn, or cyano;
wherein Rm and Rn are each independently H or C1-4alkyl; and n is a number from zero to three;or a pharmaceutically acceptable salt thereof. |
