METHODS AND SYSTEMS FOR DETERMINING RISK OF HEART FAILURE

摘要

Provided are methods, algorithms, nomograms, and computer/software systems that can be used to accurately determine the risk of developing heart failure within a specific time period in a subject not diagnosed or presenting with heart failure. Also provided are methods, algorithms, nomograms, computer/software systems for selecting a treatment for a subject and determining the efficacy of a treatment for reducing the risk of heart failure in a subject.

主权项

1. A method for determining the risk of developing heart failure within a specific time period in a subject not diagnosed or presenting with heart failure, the method comprising:
(a) providing a set of factors relating to the subject's health comprising: presence or absence of hypertension in the subject, smoking or non-smoking behavior of the subject, serum level of soluble ST2 in the subject, age of the subject, body mass index of the subject, and presence or absence of diabetes in the subject; (b) determining a separate point value for each of the provided factors in (a); (c) adding the separate point values for each of the provided factors in (b) together to yield a total points value; and (d) determining the subject's risk of developing heart failure within a specific time period by correlating the total points value in (c) with a value on a predictor scale of risk of developing heart failure within the specific time period based on the set of factors obtained from a population of subjects not diagnosed or presenting with heart failure.