发明名称 STEM CELL THERAPY FOR CROHN'S DISEASE AND ULCERATIVE COLITIS
摘要 A therapeutic process for treating an inflammatory bowel disease (IBD) using mesenchymal stem cells includes the steps of isolating a plurality of human mesenchymal stem cells from a human patient, introducing the plurality of human mesenchymal stem cells into the human patient, reducing human pro-inflammatory cytokines, wherein the human pro-inflammatory cytokines include IL-12 and IL-18, and increasing human anti-inflammatory cytokines, wherein the human anti-inflammatory cytokines include IL-10 and TGF-beta. The human mesenchymal stem cells are isolated from an umbilical cord blood or from a human adipose tissue. The plurality of human mesenchymal stem cells is introduced into the human patient through a intravenous administration or through an enema. The plurality of human mesenchymal stem cells is reconstituted into growth factor rich plasma prior to being introduced into the human patient.
申请公布号 US2015196602(A1) 申请公布日期 2015.07.16
申请号 US201514597010 申请日期 2015.01.14
申请人 FEINERMAN Burton 发明人 FEINERMAN Burton
分类号 A61K35/28 主分类号 A61K35/28
代理机构 代理人
主权项 1. A therapeutic process for treating an inflammatory bowel disease (IBD) using mesenchymal stem cells, comprising the steps of isolating a plurality of human mesenchymal stem cells from a human patient; and introducing the plurality of human mesenchymal stem cells into the human patient.
地址 TAMPA FL US