发明名称 |
PROCESS AND COMPOSITION FOR STABILIZATION OF VULNERABLE PLAQUE UTILIZING A COMBINATION OF A STATIN AND OMEGA 3 FATTY ACIDS |
摘要 |
<p>A composition and a method of treatment utilizing a combination of statins (or HMG-CoA reductase inibitors), a class of drug used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, with mixtures of an omega-3 fatty acid formulation containing about 90% or more omega 3 fatty acids by weight including a combination of Eicosapentaenoic acid (EPA), Docosapentaenoic acid (DP A) and Docosahexaenoic acid (DHA) in a weight ratio of EPA: DHA of from 5.7 to 6.3, wherein the sum of the EPA, DHA and DPA represent about 82% by weight of the total formulation and about 92% of the total omega 3 fatty acid content of the composition, the compositions and method designed to stabilize vulnerable plaque while mediating omega-3 deficiencies in individuals in need thereof.</p> |
申请公布号 |
WO2015106177(A1) |
申请公布日期 |
2015.07.16 |
申请号 |
WO2015US10928 |
申请日期 |
2015.01.10 |
申请人 |
PIVOTAL THERAPEUTICS INC.;JACKOWSKI, GEORGE;MACSWEENEY, RACHELLE;SHAIKH, NISAR AHMAD;YANTHA, JASON;SCHINI-KERTH, VALERIE B. |
发明人 |
JACKOWSKI, GEORGE;MACSWEENEY, RACHELLE;SHAIKH, NISAR AHMAD;YANTHA, JASON;SCHINI-KERTH, VALERIE B. |
分类号 |
A61K31/20;A61K31/202;A61K31/351;A61K31/405;A61K31/505;A61K31/557 |
主分类号 |
A61K31/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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