发明名称 |
INTERNALIZING MOIETIES |
摘要 |
The present disclosure provides antibodies and antigen-binding fragments capable of penetrating cells via an ENT transporter, such as humanized antibodies. The disclosure also provides conjugates comprising the antibodies or antigen-binding fragments and a heterologous agent. The disclosure further provides methods for making and using the antibodies, antigen-binding fragments and conjugates, including humanized antibodies. |
申请公布号 |
CA2936102(A1) |
申请公布日期 |
2015.07.16 |
申请号 |
CA20152936102 |
申请日期 |
2015.01.13 |
申请人 |
VALERION THERAPEUTICS, LLC |
发明人 |
ARMSTRONG, DUSTIN D.;WAY, JEFFREY C. |
分类号 |
C07K16/18;A61K38/47;A61K39/395;A61P21/00;A61P43/00;C07K14/47;C07K19/00 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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