Materials and Methods for Improving Gastrointestinal Function

摘要

The subject invention provides therapeutic compositions, and uses thereof for the treatment or amelioration of injury to small intestine mucosa. In preferred embodiments, the composition comprises one or more nutrients and/or electrolytes that acquire or retain considerable absorptive capacity.

主权项

1. A composition for improving small intestine health, wherein the composition is formulated for enteral administration and comprises, as free amino acids, at least two amino acids selected from the group consisting of threonine, valine, tryptophan, serine, and tyrosine; and water; wherein the composition does not comprise free amino acid glutamine or a glutamine-containing dipeptide, or, if free amino acid glutamine and/or a glutamine-containing dipeptide is present, the total concentration of the free amino acid glutamine and the glutamine-containing dipeptide is less than 50 mg/l; wherein the composition does not comprise glucose or, if glucose is present, the concentration of glucose is less than 1 g/l; and wherein the composition does not comprise free amino acid methionine or a methionine-containing dipeptide.