发明名称 PEPTIDE LIBRARY AND USE THEREOF
摘要 It is intended to provide a peptide library. The present invention provides a peptide selected from the following (1) and (2): a peptide selected from the following (i) and (ii): (i) a peptide comprising the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing and further comprising amino acid sequences encoded by nucleotide positions 8 to 42 and nucleotide positions 43 to 93 in the nucleotide sequence represented by SEQ ID NO: 14 in the Sequence Listing to flank the amino terminus and the carboxyl terminus, respectively, of the amino acid sequence; and (ii) a peptide comprising an amino acid sequence, derived from the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing, in which conservative amino acid substitution, deletion, addition and/or insertion of 1 to 5 (inclusive) amino acids has occurred, wherein said substitution, deletion, addition and/or insertion has occurred at amino acids other than the 1st Xaa to the 12th Xaa counting from the amino terminus.
申请公布号 US2015197546(A1) 申请公布日期 2015.07.16
申请号 US201314420317 申请日期 2013.08.07
申请人 Daiichi Sankyo Company, Limited 发明人 Nishimiya Daisuke;Hashimoto Ryuji
分类号 C07K7/08 主分类号 C07K7/08
代理机构 代理人
主权项 1. A peptide selected from the following (i) and (ii): (i) a peptide comprising an amino acid sequence encoded by a nucleotide sequence derived from SEQ ID NO: 14 in the Sequence Listing by replacing a nucleotide sequence consisting of the 43rd base thymine to the 93rd base thymine with a nucleotide sequence encoding the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing; and (ii) the peptide according to (i) having an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing by the amino acid substitution, deletion, addition, and/or insertion of 1 to 5 (inclusive) amino acids except at amino acid positions 2 to 8 and 10 to 14.
地址 Tokyo JP