发明名称 |
PEPTIDE LIBRARY AND USE THEREOF |
摘要 |
It is intended to provide a peptide library. The present invention provides a peptide selected from the following (1) and (2): a peptide selected from the following (i) and (ii): (i) a peptide comprising the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing and further comprising amino acid sequences encoded by nucleotide positions 8 to 42 and nucleotide positions 43 to 93 in the nucleotide sequence represented by SEQ ID NO: 14 in the Sequence Listing to flank the amino terminus and the carboxyl terminus, respectively, of the amino acid sequence; and (ii) a peptide comprising an amino acid sequence, derived from the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing, in which conservative amino acid substitution, deletion, addition and/or insertion of 1 to 5 (inclusive) amino acids has occurred, wherein said substitution, deletion, addition and/or insertion has occurred at amino acids other than the 1st Xaa to the 12th Xaa counting from the amino terminus. |
申请公布号 |
US2015197546(A1) |
申请公布日期 |
2015.07.16 |
申请号 |
US201314420317 |
申请日期 |
2013.08.07 |
申请人 |
Daiichi Sankyo Company, Limited |
发明人 |
Nishimiya Daisuke;Hashimoto Ryuji |
分类号 |
C07K7/08 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
1. A peptide selected from the following (i) and (ii):
(i) a peptide comprising an amino acid sequence encoded by a nucleotide sequence derived from SEQ ID NO: 14 in the Sequence Listing by replacing a nucleotide sequence consisting of the 43rd base thymine to the 93rd base thymine with a nucleotide sequence encoding the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing; and (ii) the peptide according to (i) having an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing by the amino acid substitution, deletion, addition, and/or insertion of 1 to 5 (inclusive) amino acids except at amino acid positions 2 to 8 and 10 to 14. |
地址 |
Tokyo JP |