COMPOSITIONS AND METHODS FOR HEATING NANO PARTICLES

摘要

The present disclosure provides compositions and methods for the hyperthermal activation of iron nanoparticles both in vitro and in vivo. According to one or more embodiments, light in the near infrared range (e.g., 650nm and above) may be used to heat iron nanoparticles in vivo and in vitro. For example, LumiNIR, which is a high energy light source developed for the purpose of medical and animal imaging, may be used to efficiently heat iron nanoparticles in vivo and in vitro, and hyperthermal activation of such nanoparticles may be used to sensitize various tissues for therapeutic or surgical treatment.