| 主权项 |
1. A method for predicting a predisposition to a chemoradioresistant cervical cancer in a subject, diagnosing a chemoradioresistant cervical cancer in a subject, predicting the likelihood of recurrence of cervical cancer in a cervical cancer patient previously subjected to or under a course of therapeutic treatment of said cancer, prognosis the outcome of a patient with a chemoradioresistant cervical cancer, or selecting a patient for treatment with a particular therapy, comprising:
providing a cervical cancer sample obtained from said subject, and determining the level of expression of least one gene is selected from the group consisting of RYBP, GBE1, ALG5, FAM48A, COG6, KIAA1704, GTF2F2, MED4, RNASEH2B and PRDM15 using at least one reagent that specifically binds to said gene; wherein alteration of said expression level provides an indication selected from the group consisting of an indication of a predisposition to a chemo-radioresistant cervical cancer, an indication that the subject has a chemoradioresistant cervical cancer, an indication of the likelihood of recurrence of cervical cancer, an indication of poor survival of said patient, and an indication that said subject is a candidate for treatment with a particular therapy. |
