| 发明名称 |
RNAI EXPRESSION CONSTRUCTS |
| 摘要 |
The present invention provides compositions and methods suitable for expressing 1-x RNAi agents against a gene or genes in cells, tissues or organs of interest in vitro and in vivo so as to treat diseases or disorders. |
| 申请公布号 |
US2015197751(A1) |
申请公布日期 |
2015.07.16 |
| 申请号 |
US201514673468 |
申请日期 |
2015.03.30 |
| 申请人 |
BENITEC, INC. |
发明人 |
Roelvink Petrus W.;Suhy David A.;Kolykhalov Alexander A.;Couto Linda |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A genetic construct capable of modifying expression of one or more genes, the genetic construct comprising an RNAi expression cassette comprising a promoter and two or more stem-loop structures separated by one or more spacer regions, the stem-loop structures being RNAi agents when transcribed from the promoter. |
| 地址 |
Mountain View CA US |
