| 摘要 |
PROBLEM TO BE SOLVED: To provide antimicrobial compositions useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes).SOLUTION: Antimicrobial compositions contain as a cationic antiseptic biguanide and bisbiguanide, chlorhexidine and digluconate, diacetate, dimethosulfate, and dilactate salt thereof; polymeric quaternary ammonium compounds, for example, polyhexamethylenebiguanide; silver and various silver complexes; small molecule quaternary ammonium compounds, for example, benzalkoium chloride and alkyl substituted derivatives; di-long chain alkyl (C8-C18) quaternary ammonium compounds; cetylpyridinium halides and their derivatives; benzethonium chloride and its alkyl substituted derivatives; and octenidine. The compositions also contain an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. |
