BIOREACTOR AND RACK FOR MOUNTING BIOREACTORS

摘要

A bioreactor for preferably three-dimensional cell culturing comprises a scaffold chamber, a first tube, a second tube and a first valve with a scaffold adapter, a tube adapter and a medium adapter. The first valve has a housing with a longitudinal female portion ending in an opening and a longitudinal actuator being arranged through the opening of the female portion of the housing such that the actuator is arranged partially inside the housing and partially outside the housing, wherein the actuator of the first valve is axially moveable relative to the housing of the first valve between a first position in which the first valve is in the operation position and a second position in which the first valve is in the medium change position. By providing the actuators in the first valve which is applied by axial movements, operation of the bioreactor can be comparably simple and safe. In particular, such arrangement allows for a comparably easy identification of the position of the first valve, i.e., e.g., if the valve is in the medium change position or in the operation position. Furthermore, it also allows for exactly adjusting the position of the actuator such that also positions in between the medium change position and the operation position can be conveniently applied if necessary.

主权项

1. A bioreactor for preferably three-dimensional cell culturing, comprising a scaffold chamber, a first tube, a second tube and a first valve with a scaffold adapter, a tube adapter and a medium adapter, wherein
the tube adapter of the first valve is connected to the first tube and the scaffold adapter of the first valve is connected to the scaffold chamber; the first valve is arrangeable in an operation position in which the scaffold adapter of the first valve is in fluid connection with the tube adapter of the first valve and the medium adapter of the first valve is fluid sealed to the tube adapter of the first valve; and the first valve is arrangeable in a medium change position in which the medium adapter of the first valve is in fluid connection with the tube adapter of the first valve and the scaffold adapter of the first valve is fluid sealed to the tube adapter of the first valve; wherein the first valve has a housing with a longitudinal female portion ending in an opening and a longitudinal actuator being arranged through the opening of the female portion of the housing such that the actuator is arranged partially inside the housing and partially outside the housing, wherein the actuator of the first valve is axially moveable relative to the housing of the first valve between a first position in which the first valve is in the operation position and a second position in which the first valve is in the medium change position.