| 发明名称 |
Stable Aqueous Formulations of Etanercept |
| 摘要 |
The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same. |
| 申请公布号 |
US2015196645(A1) |
申请公布日期 |
2015.07.16 |
| 申请号 |
US201514592654 |
申请日期 |
2015.01.08 |
| 申请人 |
COHERUS BIOSCIENCES, INC. |
发明人 |
Manning Mark;Murphy Brian |
| 分类号 |
A61K47/26;A61K47/10;A61K47/22;A61K47/02;C07K14/705;A61K47/18 |
主分类号 |
A61K47/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stabilized aqueous pharmaceutical composition having long term storage stability, comprising: etanercept and a stabilizer to inhibit instability, aggregation and/or fragmentation of the etanercept, wherein the composition is free or essentially free of arginine as a stabilizer. |
| 地址 |
REDWOOD CITY CA US |
