发明名称 |
Composition for proteasome inhibition |
摘要 |
<p>Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed:</p> |
申请公布号 |
EP2261236(B1) |
申请公布日期 |
2015.07.15 |
申请号 |
EP20100179422 |
申请日期 |
2005.12.07 |
申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
LEWIS, EVAN R.;HO, MARK NGUYEN;FONSECA, FABIANA N. |
分类号 |
A61K38/14;C07K5/087 |
主分类号 |
A61K38/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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