发明名称 COMPOSITIONS AND METHODS FOR INHIBITING HYPOXIA INDUCED DAMAGE
摘要 Provided are compositions and methods for inhibiting hypoxia-induced damage. The compositions and methods involve the use of one or more agents that can inhibit one or any combination of the genes BCL2L14, BLOC1S2, C20RF42, CPT1A, FBP1, GCNT3, RHOB, SCIN, TACR1 and TNFAIP6. Polynucleotide and non-polynucleotide agents which can be used for inhibiting one or more of the genes are included. The method involves introducing one or more gene inhibiting agents to a cell, tissue, organ, or individual such that formation of hypoxia related damage is inhibited. Kits which contain the agents and printed information about using them for inhibiting hypoxia induced damage are also included.
申请公布号 EP2892568(A2) 申请公布日期 2015.07.15
申请号 EP20130835605 申请日期 2013.09.05
申请人 HEALTH RESEARCH, INC.;F.HOFFMANN-LA ROCHE AG 发明人 KANDEL, EUGENE;ZYNDA, EVAN;SCHOTT, BRIGITTE
分类号 A61K38/00;A61K48/00;C12N15/11 主分类号 A61K38/00
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