| 发明名称 | Transdermal delivery system | ||
| 摘要 | A transdermal delivery system comprising a composition comprising a physiologically active agent and a penetration enhancer wherein the penetration enhancer comprises a combination of (i) an ester of salicylic acid, preferably selected from the C6 to C30 aliphatic ester of salicylic acid and (ii) polyethylene glycol (PEG) of average molecular weight no more than 300. | ||
| 申请公布号 | US9078810(B2) | 申请公布日期 | 2015.07.14 |
| 申请号 | US201313887758 | 申请日期 | 2013.05.06 |
| 申请人 | ACRUX DDS PTY LTD | 发明人 | Setiawan Kerrie;Watkinson Adam |
| 分类号 | A61K9/00;A61K9/12;A61K31/56;A61K31/57;A61K47/10;A61K31/565;A61K31/568;A61K31/573;A61M35/00;A61K47/14;A61K47/32 | 主分类号 | A61K9/00 |
| 代理机构 | Foley & Lardner LLP | 代理人 | Foley & Lardner LLP |
| 主权项 | 1. A transdermal delivery system comprising a composition comprising (a) a physiologically active agent; (b) a penetration enhancer comprising a combination of (i) a C6 to C12 alkyl ester of salicylic acid in an amount from 0.1% to 10% by weight of the composition and(ii) a polyethylene glycol having an average molecular weight of no more than 300 in an amount from 0.5% to 20% by weight of the composition wherein the weight ratio of the C6 to C12 alkyl ester of salicylic acid to the polyethylene glycol is from 10:1 to 1:10; and (c) a volatile solvent selected from the group consisting of C2 to C4 alkanols in an amount from 70% to 95% by weight of the composition. | ||
| 地址 | West Melbourne, Victoria AU | ||