发明名称 Herbicidally and fungicidally active 3-phenylisoxazoline-5-carboxamides and 3-phenylisoxazoline-5-thioamides
摘要 3-Phenylisoxazoline-5-carboxamides and 3-phenylisoxazoline-5-thioamides of the formula (I) and their use as herbicides and fungicides are described.;;In this formula (I), X, X2 to X6, R1 to R4 are radicals such as hydrogen, halogen and organic radicals such as substituted alkyl. A is a bond or a divalent unit. Y is a chalcogen.
申请公布号 US9078442(B2) 申请公布日期 2015.07.14
申请号 US201214006280 申请日期 2012.03.26
申请人 BAYER INTELLECTUAL PROPERTY GMBH 发明人 Willms Lothar;Schmitt Monika H;Frenzel Thomas;Haaf Klaus Bernhard;Häuser-Hahn Isolde;Heinemann Ines;Gatzweiler Elmar;Rosinger Christopher Hugh;Kehne Heinz;Dittgen Jan;Feucht Dieter;Hills Martin Jeffrey;Rinolfi Philippe
分类号 A01N25/32;A01N43/40;A01N43/36;A01N43/54;A01N43/82;A01N43/78;A01N43/80;A61K31/505;A61K31/44;A61K31/41;A61K31/425;A61K31/42;C07D239/24;C07D401/02;C07D261/02;C07D413/02;C07D285/08;C07D271/06;C07D413/04;A01N43/56;C07D261/04;C07D413/12;C07D417/12 主分类号 A01N25/32
代理机构 Miles & Stockbridge, P.C. 代理人 Miles & Stockbridge, P.C.
主权项 1. A 3-phenylisoxazoline-5-carboxamide or 3-phenylisoxazoline-5-thioamide of formula (I) and/or a salt thereof in which R1 and R2 independently of one another are each hydrogen, fluorine, chlorine, bromine, iodine, cyano, or (C1-C4)-alkyl or (C1-C4)-alkoxy substituted by in each case m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine and cyano, or R1 and R2 together with the carbon atom to which they are attached form a saturated, partially or fully unsaturated three-, four- or 5-membered ring which is constructed of q carbon atoms and p oxygen atoms; R3 is fluorine, chlorine, cyano, (C1-C3)-alkylcarbonyloxy or S(O)nR5, or (C1-C6)-alkyl, (C3-C6)-cycloalkyl, (C2-C6)-alkenyl or (C2-C6)-alkynyl substituted by in each case m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano, (C1-C4)-alkoxy and hydroxy, or (C1-C6)-alkylcarbonyl, (C2-C6)-alkenylcarbonyl or (C3-C6)-cycloalkylcarbonyl substituted by in each case m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano and (C1-C6)-alkoxy; R4 is hydrogen, cyano, or (C1-C8)-alkyl or (C3-C8)-cycloalkyl substituted by in each case m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano, hydroxy and (C1-C6)-alkoxy; A is a bond or a divalent unit from the group consisting of R10, R11, R12, R13, R14 and R15 are each independently of one another hydrogen, fluorine, chlorine, bromine, iodine, hydroxy, cyano, CO2R8, CONR6R8, R5, or (C1-C6)-alkyl, (C3-C5)-cycloalkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, hydroxy and cyano; or (C1-C6)-alkoxy, (C3-C6)-cycloalkoxy, (C2-C6)-alkenyloxy or (C2-C6)-alkynyloxy, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano and (C1-C2)-alkoxy, Y is oxygen or sulfur; X is hydrogen, cyano, hydroxy, X1, or(C1-C12)-alkyl, (C3-C8)-cycloalkyl, (C2-C12)-alkenyl or (C2-C12)-alkynyl substituted by in each case m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano, hydroxy, OR7, X1, OX1, NHX1, S(O)nR5, SO2NR6R7, SO2NR6R8, CO2R8, CONR6R8, COR6, CONR8SO2R5, NR6R8, NR6COR8, NR6CONR8R8, NR6CO2R8, NR6SO2R8, NR6SO2NR6R8, OCONR6R8, OCSNR6R8, POR9R9 and C(R6)═NOR8,orX, A and R4 together with the nitrogen atom to which they are attached form a saturated, partially or fully unsaturated five-, six- or seven-membered ring which, in addition to this nitrogen atom, contains k carbon atoms, n oxygen atoms, p sulphur atoms and p elements selected from the group consisting of NR7 and NCOR7 as ring atoms, where a carbon atom carries p oxo groups; X1 is a 5- or 6-membered saturated, partially unsaturated, fully unsaturated or aromatic ring which is constructed of r carbon atoms, s nitrogen atoms, n sulphur atoms and n oxygen atoms and which is substituted by n radicals selected from the group consisting of R6, R6a, R8 and R9; X2, X4 and X6 independently of one another are each hydrogen, fluorine, chlorine, bromine, iodine, cyano, nitro, or (C1-C4)-alkyl, (C3-C5)-cycloalkyl, (C2-C4)-alkenyl, (C2-C4)-alkynyl, (C1-C4)-alkoxy, (C2-C4)-alkenyloxy, (C2-C4)-alkynyloxy or (C1-C4)-alkylcarbonyl, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano and (C1-C4)-alkoxy; X3 is fluorine, chlorine, bromine, iodine, hydroxy, cyano, nitro, SF5, CONR8SO2R5, CONR6R8, COR6, CO2R8, CONR6R8, C(R6)═NOR8, NR6COR8, NR6CONR8R8, NR6CO2R8, NR6SO2R8, NR6SO2NR6R8, OCONR6R8, OSO2R5, R5, S(O)nR5, SO2NR6R8, OSO2NR6R8, or (C1-C6)-alkyl, (C3-C5)-cycloalkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, hydroxy and cyano,or (C1-C6)-alkoxy, (C3-C6)-cycloalkoxy, (C2-C6)-alkenyloxy or (C2-C6)-alkynyloxy, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano and (C1-C2)-alkoxy, X5 is hydrogen or X3; R5 is (C1-C6)-alkyl or (C3-C6)-cycloalkyl, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, iodine, cyano and hydroxy; R6 is hydrogen or R5; R6a is fluorine, chlorine, bromine, iodine, cyano, hydroxy, S(O)nR5 or (C1-C6)-alkoxy, (C2-C6)-alkenyloxy or (C3-C6)-alkynyloxy, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, cyano and (C1-C2)-alkoxy; R7 is hydrogen or (C1-C6)-alkyl, (C3-C6)-cycloalkyl, (C2-C4)-alkenyl or (C2-C4)-alkynyl, each of which is substituted by m radicals selected from the group consisting of fluorine, chlorine, bromine, cyano and (C1-C2)-alkoxy; R8 is R7; R9 is (C1-C3)-alkyl or (C1-C3)-alkoxy; k is 3, 4, 5 or 6; m is 0, 1, 2, 3, 4 or 5; p is 0 or 1; q is 3, 4 or 5; r is 1, 2, 3, 4 or 5; s is 0, 1, 2, 3, or 4; with the proviso that X3 and X4 are not both substituted or unsubstituted alkoxy.
地址 Monheim DE