| 发明名称 | Synthesis of a glycosyltransferase inhibitor | ||
| 摘要 | Process for the preparation of an iminosugar, and the intermediates thereof, having known activity as a glycosyltransferase inhibitor and used, for example, in the treatment of Gaucher's disease. | ||
| 申请公布号 | US9079856(B2) | 申请公布日期 | 2015.07.14 |
| 申请号 | US201314097398 | 申请日期 | 2013.12.05 |
| 申请人 | Dipharma Francis S.r.l. | 发明人 | Attolino Emanuele;Malvestiti Andrea |
| 分类号 | C07D211/46;C07D211/40 | 主分类号 | C07D211/46 |
| 代理机构 | Rothwell, Figg, Ernst & Manbeck, P.C. | 代理人 | Rothwell, Figg, Ernst & Manbeck, P.C. |
| 主权项 | 1. A compound of formula (III), namely N-butyl 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol, in crystalline Form A, having an XRPD spectrum as shown in FIG. 1, wherein the most intense peaks (expressed in 2θ) are to be found at: 4.83, 5.76, 6.96, 7.80, 13.08, 16.50, 17.97, 18.75, 19.14, and 19.62. | ||
| 地址 | Baranzate (MI) IT | ||