发明名称 BIOMARKER FOR PATIENT MONITORING
摘要 FIELD: medicine.SUBSTANCE: group of inventions relates to medicine, namely to immunology, and can be used for the ex-vivo determination of the cancer treatment efficiency. For this purpose, a level of activated T-lymphocytes (CD3+ CD69+) in an organism is measured after the introduction to a subject of one or more doses of an immunogenic composition. The level of the activated T-lymphocytes (CD3+ CD69+) higher than approximately 10.4% testifies to the fact that the subject is such that demonstrates successful clinical outcome for treatment; that is an increase of the survival rate.EFFECT: application of the level of the activated T-lymphocytes (CD3+ CD69+) makes it possible to apply them as a biomarker for the monitoring, modification or correction of cancer treatment.7 cl, 1 ex, 2 dwg
申请公布号 RU2555340(C2) 申请公布日期 2015.07.10
申请号 RU20110146419 申请日期 2010.04.12
申请人 TRANSZHENE SA 发明人 BRJUS AKRE
分类号 G01N33/533 主分类号 G01N33/533
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