IMPROVED PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE LINEZOLID FORM -1

摘要

The invention relates to enantiomeric pure linezolid Form-I having S-isomer content more than about 99.9% relative to its R-isomer. Further aspect of invention provides the improved process for preparation of enantiomeric pure linezolid Form-I, wherein linezolid Form-I having the purity more than 99.9% relative to any other known polymorphic form of linezolid. The obtained enantiomeric pure linezolid Form-I of formula-I can be subsequently converted into the other known polymorphic forms linezolid.