Lactobacillus johnsonii La1 NCC533 (CNCM 1-1225) AND IMMUNE DISORDERS

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates for composition for treatment or prevention of disorders, associated with reduced level of defensins. Composition contains from 0.005 to 1000 mg of Lactobacillus johnsonii Lal (NCC533, No CNCM 1-1225) per a daily dose, with at least 90% of L. johnsonii Lal (NCC533, No CNCM 1-1225) being transferred into state in which they become non-replicating at temperature110-140°C for 5-30 s.EFFECT: invention provides enhancement of expression of defensin hBD1 mRNA.5 cl, 2 dwg