Methods, Systems, and Devices Relating to Directional Eluting Implantable Medical Devices

摘要

Implantable medical devices may directionally elute a first therapeutic agent that promotes the growth of endothelial cells and a second therapeutic agent that inhibits the growth of smooth muscle cells. In some embodiments, implantable medical devices may elute a first therapeutic agent such as an anti-proliferative drug from an abluminal side of the implantable medical device and a second therapeutic agent such as an endothelialization agent from a luminal side of the implantable medical device.

主权项

1. An implantable medical device comprising:
a device body having a luminal surface and an abluminal surface; a first coating disposed on the abluminal surface, the first coating configured to elute an antiproliferative drug; and a second coating disposed on the luminal surface, the second coating configured to elute an endothelialization promotion agent.