发明名称 |
ENHANCED PROTEIN EXPRESSION |
摘要 |
The present invention relates in general to bacterial cells having a genetic alteration that results in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include Gram positive microorganisms, such as Bacillus species, having a genetic alteration that reduces the expression of a gene in the pdh operon and results in enhanced expression of a protein of interest. |
申请公布号 |
CA2935063(A1) |
申请公布日期 |
2015.07.09 |
申请号 |
CA20142935063 |
申请日期 |
2014.12.05 |
申请人 |
DANISCO US INC. |
发明人 |
BONGIORNI, CRISTINA;SCHMIDT, BRIAN F.;VAN KIMMENADE, ANITA |
分类号 |
C07K14/32;C12N15/75 |
主分类号 |
C07K14/32 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|