| 发明名称 |
SYSTEMS AND METHODS TO DETECT BIOFILM STREAMER GROWTH AND THEIR USES |
| 摘要 |
The present invention relates to a method of measuring biofilms and/or biofilm streamers, wherein the method comprises a system that has at least one channel and a biofilm streamer promotion element, a fluid capable of moving along the channel, wherein the fluid has a flow driven by a controlled pressure; and a measuring element capable of measuring a flow rate of the fluid through the channel. Additionally, method of screening for compound(s) that promote and/or inhibit biofilm and/or biofilm streamers using this system are also contemplated. Uses of the system, methods and identified compounds are contemplated for medical and/or industrial environments. |
| 申请公布号 |
US2015191765(A1) |
申请公布日期 |
2015.07.09 |
| 申请号 |
US201514589845 |
申请日期 |
2015.01.05 |
| 申请人 |
The Trustees of Princeton University |
发明人 |
Bassler Bonnie L.;Stone Howard A.;Semmelhack Martin F.;Drescher Knut;Shen Yi;O'Loughlin Colleen T.;Miller Laura C. |
| 分类号 |
C12Q1/18;C12Q1/02 |
主分类号 |
C12Q1/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A system for measuring biofilm streamers comprising:
a. at least one channel, wherein the channel comprises an inlet, an outlet, a lumen, and at least one biofilm streamer promotion element; b. a fluid capable of moving along the channel, wherein the fluid has a flow driven by a controlled pressure; and c. a measuring element capable of measuring a flow rate of the fluid through the channel. |
| 地址 |
Princeton NJ US |
