发明名称 |
Compounds |
摘要 |
The invention relates to new derivatives of 5-aminolevulinic acid (5-ALA) and their use as photosensitizing agents. In particular, it relates to compounds of general formula I and their pharmaceutically acceptable salts, to methods for preparing such compounds and their medical and cosmetic use, for example in methods of photodynamic therapy and diagnosis:;;wherein
R1 represents a hydrogen atom or an optionally substituted alkyl or cycloalkyl group;
R2, each of which may be the same or different, represents a hydrogen atom or an optionally substituted alkyl group; and
X is a linking group. |
申请公布号 |
US2015191419(A1) |
申请公布日期 |
2015.07.09 |
申请号 |
US201314419125 |
申请日期 |
2013.08.02 |
申请人 |
Photocure ASA |
发明人 |
Brænden Jon Erik;Charnock Colin Barry;Godal Aslak;Klaveness Jo;Nilsen Nils Olav |
分类号 |
C07C229/24;A61K41/00;C07C229/22 |
主分类号 |
C07C229/24 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of general formula I, or a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or an optionally substituted alkyl or cycloalkyl group; R2, each of which may be the same or different, represents a hydrogen atom or an optionally substituted alkyl group; and X is a linking group. |
地址 |
Oslo NO |