发明名称 |
METHOD FOR SIMULTANEOUS INDUCTION OF CTL AND GAMMA DELTA T CELL |
摘要 |
<p>Disclosed are: a method for culture of disease antigen specific CTLs and ³´T cells in one culture step conveniently and efficiently; and a pharmaceutical agent and a therapeutic/prophylactic method both of which use a cell produced by the method. Blood is collected and peripheral blood mononuclear cells are separated from the blood. Aminobisphosphonate and a disease antigen are added to the peripheral blood mononuclear cells at the beginning of culture, and the cell culture is carried out for a predetermined period to proliferate/induce disease antigen specific CTLs and ³´T cells simultaneously until the numbers of the cells reach values that are effective for the treatment of a disease. The CTLs and the ³´T cells thus produced are used for the treatment.</p> |
申请公布号 |
PT2311470(E) |
申请公布日期 |
2015.07.09 |
申请号 |
PT20090773177T |
申请日期 |
2009.06.30 |
申请人 |
MEDINET CO., LTD. |
发明人 |
MIE NIEDA;MAI TOMIYAMA;MASATO MUTO |
分类号 |
A61K35/14;A61K39/00;A61P35/00 |
主分类号 |
A61K35/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|