METHODS FOR THE DETECTION OF ESOPHAGEAL ADENOCARCINOMA

摘要

Methods are disclosed for detecting the likelihood that a subject will develop esophageal adenocarcinoma. Methods are also disclosed for determining if an agent is effective for treatment or prevention of esophageal adenocarcinoma in a subject. These methods include detecting a level of biglycan, myeloperoxidase, and protein S100-A9 in a biological sample from the subject administered the agent; and comparing the level of biglycan, myeloperoxidase, and protein S100-A9 to a respective control level of biglycan, myeloperoxidase, and protein S100-A9. In some embodiments, these methods also include detecting a level of annexin-A6 in a biological sample from the subject; and comparing the level of annexin-A6 to a respective control level of annexin-A6.