Vaccines with higher carbohydrate antigen density and novel saponin adjuvant
摘要
<p>The present invention provides vaccines comprising carbohydrate antigen conjugated to a diphtheria toxin (DT) as a carrier protein, wherein the ratio of the number of carbohydrate antigen molecule to the carrier protein molecule is higher than 5:1. Also disclosed herein is a novel saponin adjuvant and methods to inhibit cancer cells, by administering an effective amount of the vaccine disclose herein.</p>
申请公布号
AU2014203977(A1)
申请公布日期
2015.07.09
申请号
AU20140203977
申请日期
2014.01.06
申请人
OBI PHARMA INC.
发明人
LEE, WEI HAN;WANG, NAN-HSUAN;CHANG, CHUNG HAO;HSIEH, YIH-HUANG;WANG, CHENG-CHI;LIN, YU-HSIN;LIN, YU-CHEN;CHEN, I-JU;YU, CHENG DER TONY