| 发明名称 |
COMBINATION PRODUCTS FOR TREATING CANCER |
| 摘要 |
The present invention concerns products containing (i) at least one nucleic acid sequence coding for the human somatostatin 2 receptor protein (sst2) having the sequence SEQ ID NO: 1, ortholog or derivative thereof, (ii) at least one nucleic acid sequence coding for the human deoxycytidine kinase protein (dck) having the sequence SEQ ID NO:2, ortholog or derivative thereof, (iii) at least one nucleic acid sequence coding for the human uridine monophosphate kinase protein (umk) having the sequence SEQ ID NO: 3 ortholog or derivative thereof, and (iv) gemcitabine, as a combined preparation for simultaneous, separate, or sequential use for treating cancer in a subject. |
| 申请公布号 |
US2015190480(A1) |
申请公布日期 |
2015.07.09 |
| 申请号 |
US201514588585 |
申请日期 |
2015.01.02 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ;CAYLA |
发明人 |
BUSCAIL LOUIS;TIRABY GERARD;VERNEJOUL FABIENNE;SUSINI CHRISTIANE;DROCOURT DANIEL |
| 分类号 |
A61K38/45;A61K38/17;A61K47/48;A61K31/7068 |
主分类号 |
A61K38/45 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. A method for treating cancer comprising the simultaneous, separate, or sequential administration of:
(i) at least one nucleic acid sequence coding for the human somatostatin 2 receptor protein (sst2) comprising the sequence SEQ ID NO:1, or an ortholog or derivative thereof, (ii) at least one nucleic acid sequence coding for the human deoxycytidine kinase protein (dck) comprising the sequence SEQ ID NO:2, or an ortholog or derivative thereof, (iii) at least one nucleic acid sequence coding for the human uridine monophosphate kinase protein (umk) comprising the sequence SEQ ID NO:3, or an ortholog or derivative thereof, and (iv) gemcitabine, to a patient in need thereof. |
| 地址 |
PARIS FR |
