发明名称 COMPOUNDS FROM THE FRUITS OF ACROCOMIA CRISPA AND ACROCOMIA ACULEATA FOR USE AGAINST OXIDATIVE STRESS AND INFLAMMATION
摘要 This invention is related to the obtainment of a new active ingredient and its obtaining process from green or ripe fruits of both Acrocomia crispa and Acrocomia aculeata species of the Arecaceae family. Such active ingredient can be used as nutritional supplement, cosmetic-therapeutic formulations, or as pharmaceutical compositions for preventing and/or treating inflammatory processes and oxidative stress, and includes a mixture of fatty acids from 6 to 28 carbon atoms (free and/or as acylglycerols or ethyl esters), mainly those saturated of linear chain with 8, 10, 12, 14, 16 and 18 carbon atoms, and those unsaturated of 16 and 18 carbon atoms, and that may also contain sterols and fatty alcohols.
申请公布号 US2015190358(A1) 申请公布日期 2015.07.09
申请号 US201314408443 申请日期 2013.06.17
申请人 Centro Nacional De Investigaciones Cientificas (CNIC) 发明人 Canavaciolo Victor Luis Gonzales;Perez Roxana de la Caridad Sierra;Ferreiro Rosa Maria Mas;Guerra Yohani Perez;Yera Ambar Oyarzabal;Rodriguez Leyes Eduardo Antonio;Cuevas Vivian Molina;Menendez Rafael Gamez
分类号 A61K31/201;A61K36/889;A61K31/20 主分类号 A61K31/201
代理机构 代理人
主权项 1. An active ingredient obtained from the fruits of at least one of Acrocomia crispa and Acrocomia aculeata species, of the Arecaceae family, which contains a mixture of fatty acids from 6 to 28 carbon atoms (free or as acylglycerols or ethyl esters), and that also may contain sterols and high molecular weight fatty alcohols, and that mainly includes the following acids: caprilic (C8:0), capric (C10:0), lauric (C12:0), myristic (C14:0), palmitic (C16:0), palmitoleic (C16:1), stearic (C18:0), oleic (C18:1), linoleic (C18:2) and linolenic (C18:3) acids in the following proportions:AcidContent (%)caprilic acid (C8:0)<3.0capric acid (C10:0)<3.0lauric acid (C12:0)30.0-40.0myristic acid (C14:0) 8.0-15.0palmitic acid (C16:0) 5.0-12.0paimitoleic acid (C16:1)<3.0stearic acid (C18:0)1.0-5.0oleic acid (C18:1) *  20.0-35.0 ** Determined and reported as oleic acid, includes the mixture of oleic C18:1(60-70%); linoleic C18:2(25-40%) and linolenic C18:3 (<10%) acids.
地址 La Habana CU