BONE REGENERATION MATERIAL

摘要

A method of manufacturing a bone substitute structure for reconstruction of bone material in a patient. The method comprises the steps of providing data reflecting a cavity in a bone of a patient, defining and modelling a three dimensional structure corresponding to the cavity in the bone; and providing an individualized bone substitute structure, corresponding to the defined and modeled three dimensional structure, by combining calcium phosphate cement, growth factors and the patient's own un-coagulated blood.

主权项

1. A method of manufacturing a bone substitute structure in reconstruction of bone material in a patient, the method comprising:
I. providing data reflecting a cavity in a bone of a patient; II. defining and modelling a three dimensional structure corresponding to the cavity in the bone; and III. providing an individualized bone substitute structure, corresponding to the defined and modeled three dimensional structure in II, by combining calcium phosphate cement, growth factors and the patient's own un-coagulated blood, wherein the individualized bone substitute structure in III is obtained by using a rapid prototype machine to generate the individualized bone substitute structure by additive layer manufacturing, wherein a layer upon layer sequence of the calcium phosphate cement, the individualized growth factors and the individualized un-coagulated blood prints the individualized bone substitute structure, and wherein the rapid prototype machine comprises at least a first printing tube for the calcium phosphate cement, a second printing tube for the individualized un-coagulated blood and a third printing tube for the growth factors, wherein these at least three printing tubes are computer controlled regarding flow-rate and the layer upon layer sequence.