| 发明名称 |
POLYMERIC NANOPARTICLES IN A THERMOSENSITIVE GEL FOR COITAL-INDEPENDENT VAGINAL PROPHYLAXIS OF HIV |
| 摘要 |
An antiretroviral composition that gels upon heating and can be administered prophylactically prior to exposure to a retrovirus following sexual intercourse, and methods of using the same. |
| 申请公布号 |
US2015190398(A1) |
申请公布日期 |
2015.07.09 |
| 申请号 |
US201314422747 |
申请日期 |
2013.07.31 |
| 申请人 |
Creighton University |
发明人 |
Destache Chris;Date Abhijit;Shibata Annemarie |
| 分类号 |
A61K31/536;A61K9/06;A61K47/10;A61K31/513 |
主分类号 |
A61K31/536 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An antiretroviral composition that gels when heated to a temperature of about 30° C. to about 33° C. and can be administered prophylactically up to and including seven days prior to exposure to the retrovirus, the composition comprising: a) a mixture of thermosensitive polymers, and (b) a nanoparticle comprising a biodegradable polymer and at least one antiretroviral drug. |
| 地址 |
Omaha NE US |
