COMPOSITIONS AND METHODS FOR INHIBITING ACTIVITY OF HYPOXIA-INDUCIBLE TRANSCRIPTION FACTOR COMPLEX AND ITS USE FOR TREATMENT OF TUMORS
摘要
Disclosed are epidithiodiketopiperazine compounds, pharmaceutical compositions based thereon and methods of treating, reducing or inhibiting transcription and translation of hypoxia-inducible genes.
申请公布号
EP2890382(A1)
申请公布日期
2015.07.08
申请号
EP20130832341
申请日期
2013.03.15
申请人
UNIVERSITY OF SOUTHERN CALIFORNIA
发明人
OLENYUK, BOGDAN, Z.;DUBEY, RAMIN;LEVIN, MICHAEL, D.
