The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
申请公布号
EP2164967(B1)
申请公布日期
2015.07.08
申请号
EP20080756453
申请日期
2008.05.29
申请人
UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人
DAVIDSON, BEVERLY, L.;MAS MONTEYS, ALEJANDRO;MCBRIDE, JODI, L.;BOUDREAU, RYAN