摘要 |
<p>Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis.</p> |
申请人 |
THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LIU, DAVID, R.;GARTNER, ZEV, J.;DOYON, JEFFREY, B.;CALDERONE, CHRISTOPHER, T.;KANAN, MATTHEW, W.;LI, XIAOYU;SNYDER, THOMAS, M.;ROSENBAUM, DANIEL, M. |